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Impurities in Pharmaceutical Analysis: Types, Sources, USP & ICH Guidelines, and Advanced Profiling Explained

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What is Impurity? Impurities defined as a foreign particle that affects the purity of a substance. Impurities are chemical substances inside a confined amount of liquid, gas, or solid, which differ from the chemical composition of the material or compound. Impurities in pharmaceuticals are the unwanted chemicals that remain with the active pharmaceutical ingredients (APIs), or develop during formulation. The presence of these […]

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Preparation and Standardization of Various Molar and Normal Solutions

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Introduction In every chemistry and pharmaceutical analysis laboratory, the preparation of accurate solutions is one of the most important tasks. Whether we are working on titration, drug analysis, water testing, or industrial quality control, the results always depend on how well the solutions are prepared and standardized. A standard solution is simply a solution of

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Primary and Secondary Standards in Pharmaceutical Analysis

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When we talk about standards, we usually mean a pure substance that is used to prepare solutions of exactly known strength. In simple words, a standard is a “reference chemical” in laboratory work. Standards are mainly of two types: Now, let us understand both in detail. What is a Primary Standard? A primary standard is a highly pure

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Pharmaceutical analysis – Definition and scope

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What is Pharmaceutical Analysis? Pharmaceutical Analysis involves the identification, determination, and purification of a substance, the separation of components in a mixture, or the determination of structure of chemical compounds used in pharmaceutical production. It is used to check the quality of raw materials, in-process materials, and finished products. Importance of Pharmaceutical Analysis Basic Concepts

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